Alcohol consumption is associated with an increased risk of erosive esophagitis and Barrett's epithelium in Japanese men.

ABSTRACT:

Background

Evidence regarding the association between alcohol consumption and the gastro-esophageal reflux disease (GERD) spectrum has been conflicting. We examined the association between alcohol consumption and erosive esophagitis and Barrett's epithelium in Japanese men.

Methods

The study population comprised 463 men subjects who had undergone an upper endoscopy at the Gastroenterology Division of Yokohama City University Hospital between August 2005 and July 2006. The presence of erosive esophagitis and Barrett's epithelium was diagnosed based on the Los Angeles Classification and the Prague C and M Criteria, respectively. We divided the study population into four groups: never drinkers, light drinkers (less than 25.0 g of ethanol per day), moderate drinkers (25.0 to 50.

SUBMITTER: Akiyama T 

PROVIDER: S-EPMC2615024 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature