ExonMiner: Web service for analysis of GeneChip Exon array data.

ABSTRACT:

Background

Some splicing isoform-specific transcriptional regulations are related to disease. Therefore, detection of disease specific splice variations is the first step for finding disease specific transcriptional regulations. Affymetrix Human Exon 1.0 ST Array can measure exon-level expression profiles that are suitable to find differentially expressed exons in genome-wide scale. However, exon array produces massive datasets that are more than we can handle and analyze on personal computer.

Results

We have developed ExonMiner that is the first all-in-one web service for analysis of exon array data to detect transcripts that have significantly different splicing patterns in two cells, e.g. normal and cancer cells. ExonMiner can perform the following analyses: (1) data norm

SUBMITTER: Numata K 

PROVIDER: S-EPMC2621370 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature