Model of reentrant ventricular tachycardia based on infarct border zone geometry predicts reentrant circuit features as determined by activation mapping.

ABSTRACT:

Background

Infarct border zone (IBZ) geometry likely affects inducibility and characteristics of postinfarction reentrant ventricular tachycardia, but the connection has not been established.

Objective

The purpose of this study was to determine characteristics of postinfarction ventricular tachycardia in the IBZ.

Methods

A geometric model describing the relationship between IBZ geometry and wavefront propagation in reentrant circuits was developed. Based on the formulation, slow conduction and block were expected to coincide with areas where IBZ thickness (T) is minimal and the local spatial gradient in thickness (DeltaT) is maximal, so that the degree of wavefront curvature rho proportional, variant DeltaT/T is maximal. Regions of fastest conduction velocity were pre

SUBMITTER: Ciaccio EJ 

PROVIDER: S-EPMC2626544 | biostudies-literature | 2007 Aug

REPOSITORIES: biostudies-literature