A study on the differential protein profiles in liver cells of heat stress rats with and without turpentine treatment.

ABSTRACT:

Background

Heat stress (HS) and related illnesses are a major concern in military, sports, and fire brigadiers. HS results in physiologic responses of increased temperature, heart rate and sweating. In heat stroke, inflammatory response plays an important role and it is evidenced that turpentine (T) induced circulating inflammatory cytokines reduced survival rate and duration at 42 degrees C. Here we report the alteration in the protein expression in liver cells upon HS with and without T treatment using two dimensional gel electrophoresis (2-DE), tryptic in-gel digestion and MALDI-TOF-MS/MS approaches.

Results

The effects of HS and T treatments alone and a combined treatments (T+HS) was performed in Wistar rat models. Proteomic analysis of liver in the HS and T+HS groups we

SUBMITTER: Rajaseger G 

PROVIDER: S-EPMC2626589 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature