Project description:Modern automotive press shops are reaching their process limits due to increasing demands on car body shapes. At the same time, transmission of information and readjustment in the event of quality losses because of process errors is still largely controlled manually. The survey presented here, deals with better connected processes as well as data acquisition, and track and trace applications in press shops. The survey was directed to experts from the automotive industry and is to determine how automated and connected the processes in press shops already are. The survey was conducted from March till April 2020. With a total of 24 questions, an attempt is made to gain a comprehensive picture of the current status and the existing potential regarding smart press shops. In addition to questions on the marking and tracking of pressed parts, the objective is to find out which process data is already being recorded today and what conclusions can be drawn from it regarding the expected part quality. The evaluation of the survey is intended to build the basis for research activities on smart, connected press shops.
Project description:BackgroundThe bench press exercise (BP) plays an important role in recreational and professional training, in which muscle activity is an important multifactorial phenomenon. The objective of this paper is to systematically review electromyography (EMG) studies performed on the barbell BP exercise to answer the following research questions: Which muscles show the greatest activity during the flat BP? Which changes in muscle activity are related to specific conditions under which the BP movement is performed?StrategyPubMed, Scopus, Web of Science and Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library were searched through June 10, 2016. A combination of the following search terms was used: bench press, chest press, board press, test, measure, assessment, dynamometer, kinematics and biomechanics. Only original, full-text articles were considered.ResultsThe search process resulted in 14 relevant studies that were included in the discussion. The triceps brachii (TB) and pectoralis major (PM) muscles were found to have similar activity during the BP, which was significantly higher than the activity of the anterior deltoid. During the BP movement, muscle activity changes with exercise intensity, velocity of movement, fatigue, mental focus, movement phase and stability conditions, such as bar vibration or unstable surfaces. Under these circumstances, TB is the most common object of activity change.ConclusionsPM and TB EMG activity is more dominant and shows greater EMG amplitude than anterior deltoid during the BP. There are six factors that can influence muscle activity during the BP; however, the most important factor is exercise intensity, which interacts with all other factors. The research on muscle activity in the BP has several unresolved areas, such as clearly and strongly defined guidelines to perform EMG measurements (e.g., how to elaborate with surface EMG limits) or guidelines for the use of exact muscle models.
Project description:The transition from maternal to zygotic gene expression during zygotic genome activation (ZGA) is tightly associated with chromatin accessibility modulated by maternal transcription factors. However, due to technical limitations, it remains elusive how the chromatin regulatory landscape is established in Xenopus tropicalis ZGA, and let alone DNA binding transcription regulators involved in this process. Here, by developing concanavalin A beads-based nucleus capture followed by Tn5-mediated accessible chromatin assay with sequencing (CANTAC-seq), we generated a first genome-wide map of accessible chromatin in X. tropicalis embryos from early blastula to neurula stage. We found that open chromatin landscape is progressively established at cis-regulatory elements during ZGA. Based on the motif analysis and perturbation experiments, we demostrated E2f1, a well-known transcriptional activator, maintains a repressive chromatin environment preceding minor ZGA. Moreover, we identified another maternal factor Otx1 counteracts the inhibitory function of E2f1. Mechanistically, E2f1 and Otx1 co-regulate a set of genes required for zygotic gene transcription and germ layer differentiation before the midblastula transition (MBT) through a seesaw model. Taken together, our data reveals the dynamic chromatin regulatory landscape that accompanies early development and elaborates on the function of a coupled transcriptional repressor-activator regulating zygotic gene transcription in a classical model organism.
Project description:Due to recent advancements and appealing applications, the purchase rate of smart devices is increasing at a higher rate. Parallely, the security related threats and attacks are also increasing at a greater ratio on these devices. As a result, a considerable number of attacks have been noted in the recent past. To resist these attacks, many password-based authentication schemes are proposed. However, most of these schemes are not screen size independent; whereas, smart devices come in different sizes. Specifically, they are not suitable for miniature smart devices due to the small screen size and/or lack of full sized keyboards. In this paper, we propose a new screen size independent password-based authentication scheme, which also offers an affordable defense against shoulder surfing, brute force, and smudge attacks. In the proposed scheme, the Press Touch (PT)-a.k.a., Force Touch in Apple's MacBook, Apple Watch, ZTE's Axon 7 phone; 3D Touch in iPhone 6 and 7; and so on-is transformed into a new type of code, named Press Touch Code (PTC). We design and implement three variants of it, namely mono-PTC, multi-PTC, and multi-PTC with Grid, on the Android Operating System. An in-lab experiment and a comprehensive survey have been conducted on 105 participants to demonstrate the effectiveness of the proposed scheme.
Project description:PurposeUnderstanding important features for performance in non-disabled bench press and Paralympic powerlifting may inform talent identification and transfer models. The aim of this scoping review was to describe features associated with bench press performance.MethodsWe conducted a systematic search of three electronic databases (PubMed, SportDiscus and EMBASE) to identify studies involving non-disabled and Para athlete populations that investigated features related to bench press one-repetition maximum (1RM), across six domains (anthropometric, body composition, demographic, technical, disability and neuromuscular). Search terms included "resistance training", "para powerlifting' and "one repetition max". No date restrictions were include in searches. Studies using adult participants, with at least six-months of bench press experience, who were able to bench press their body mass were included.ResultsThirty-two studies met our inclusion criteria. Twenty-four studies involved non-disabled athletes (total n = 2,686; 21.9% female) and eight involved Para athletes (total n = 2,364; 39.4% female). Anthropometric (17 studies) and body composition (12 studies) features were most studied; half of the 32 studies investigated features from a single domain. Of anthropometric variables, upper arm circumference shared the strongest association with bench press 1RM in non-disabled (r = 0.87) and para-athletes (r = 0.65). Upper limb fat free mass (r = 0.91) and body mass index (r = 0.46) were the body composition variables sharing the strongest association with bench press 1RM in non-disabled and para-athletes. Few studies considering the uncertainty of their results. Practices of open and transparent science, such as pre-registration and data sharing, were absent.ConclusionThe development of bench press talent identification and sport transfer models will require future studies to investigate both non-training and training modifiable features, across multiple domains. Large longitudinal studies using information from athlete monitoring databases and multivariable model approaches are needed to understand the interacting features associated with bench press performance, and for the development of talent identification models.
Project description:This systematic review and meta-analysis investigated the influence of dietary nitrate supplementation on resistance exercise performance according to the PRISMA guidelines. Searches were conducted on MEDLINE, PubMed, ScienceDirect, Scopus and SPORTDiscus databases up to April 2023. Inclusion criteria were adult resistance-trained males who supplemented with a nitrate-rich supplement and nitrate-deficient placebo to assess repetitions-to-failure (RTF), peak power, mean power, peak velocity, and/or mean velocity during back squat and bench press exercise. A random effects model was performed on six studies and showed that nitrate supplementation improved RTF (standardized mean difference [SMD]: 0.43, 95% confidence intervals [95% CI]: 0.156 to 0.699, p = 0.002), mean power (SMD: 0.40, 95% CI: 0.127 to 0.678, p = 0.004), and mean velocity (SMD: 0.57, 95% CI: 0.07 to 1.061, p = 0.025) but had no effect on peak power (SMD: 0.204, 95% CI: -0.004 to 0.411, p = 0.054) or peak velocity (SMD: 0.00, 95% CI: -0.173 to 0.173, p = 1.000) when back squat and bench press were combined. Subgroup analyses revealed that back squats were more likely to be enhanced and that a dosing regimen may influence the efficacy of nitrate supplementation. Overall, nitrate supplementation had a small beneficial effect on some aspects of resistance exercise performance, but there were limited studies available and the variability was large. Additional studies that focus on upper and lower body resistance exercise and nitrate dosage are required to elucidate the efficacy of dietary nitrate supplementation on resistance exercise performance.
Project description:Proton magnetic resonance spectroscopy measurements of glutamate and GABA are important in neuropsychiatric research. Some study designs require simultaneous measurement of both metabolites. GABA measurement requires specialized pulse sequences, the most common approach being J-difference spectral editing with MEGA-PRESS. This method enables two different strategies for concurrently measuring glutamate - from either off-resonance or difference spectra. However, it is uncertain how either strategy compares to conventional glutamate measurements. Here we compared these approaches in 49 subjects (28 healthy volunteers and 21 first-episode psychosis patients), in whom both PRESS (TE 80) and MEGA-PRESS (TE 68) spectra were obtained from dorsolateral prefrontal cortex. Glutamate and glx estimates from MEGA-PRESS difference and off-resonance spectra were compared to glutamate and glx estimates from PRESS spectra using correlational analyses. In healthy volunteers, correlations between PRESS and MEGA-PRESS off-resonance values were r ≥ 0.88 and were significantly higher than correlations between PRESS and MEGA-PRESS difference spectrum values (r ≤ 0.36). Patients showed a similar pattern. Lower correlations with difference spectrum values may reflect a disproportionate impact of field instabilities on co-edited glutamate signals. The results suggest that MEGA-PRESS off-resonance spectra can substitute for separately-acquired PRESS spectra in studies requiring simultaneous glutamate and GABA measurements.