Clarification of anomalies in the application of a 2La molecular karyotyping method for the malaria vector Anopheles gambiae.

ABSTRACT:

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Background

Chromosomal inversions have been considered to be potentially important barriers to gene flow in many groups of animals through their effect on recombination suppression in heterokaryotypic individuals. Inversions can also enhance local adaptation in different groups of organisms and may often represent species-specific differences among closely related taxa. We conducted a study to characterize the 2La inversion karyotypes of An. gambiae sensu stricto mosquitoes sampled from the Kilombero Valley (Tanzania) using a newly designed PCR assay.

Results

We frequently encountered a (687 bp) fragment which was only present in the Kilombero Valley populations. Laboratory crossing between An. gambiae s.s. from Njage (Tanzania) and Kisumu (Western Kenya)

SUBMITTER: Ng'habi KR 

PROVIDER: S-EPMC2628339 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature