Multiple myeloma and farming. A systematic review of 30 years of research. Where next?

ABSTRACT:

Background

Multiple myeloma has been linked to farming for over thirty years. However, there is little clarity about the magnitude of the risk, nor about the specific agricultural exposures which contribute to the risk.

Methods

We have carried out a systematic review of case-control studies of multiple myeloma published from 1970 to October 2007. Studies were identified through database searches and from references in the literature.Studies reporting risk estimates from farming, agricultural exposures, and exposure to animals were identified, and details abstracted. The impact of study heterogeneity, publication bias, variation in methods of case identification and exposure ascertainment between studies were considered in analysis.

Results

Case control studies showed

SUBMITTER: Perrotta C 

PROVIDER: S-EPMC2628921 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature