CTX-M expression and selection of ertapenem resistance in Klebsiella pneumoniae and Escherichia coli.

ABSTRACT: In vitro selection of mutants with decreased susceptibility to ertapenem was performed using Escherichia coli and Klebsiella pneumoniae clinical strains producing either the bla(CTX-M-2), bla(CTX-M-3), bla(CTX-M-9), or bla(CTX-M-15) gene. Frequencies of mutants with decreased susceptibilities to ertapenem were similar for all beta-lactamases expressed.

SUBMITTER: Girlich D 

PROVIDER: S-EPMC2630641 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature