Randomised aspirin assignment and risk of adult-onset asthma in the Women's Health Study.

ABSTRACT:

Background

Randomised data in men show a small but significant reduction in the risk of adult-onset asthma among those given aspirin. The results from an observational study in women suggest that frequent use of aspirin decreases the risk of adult-onset asthma, but randomised data in women are lacking. A study was undertaken to test the effect of 100 mg aspirin or placebo on alternate days on the risk of adult-onset asthma in the Women's Health Study.

Methods

A randomised, double-blind, placebo-controlled clinical trial of aspirin and vitamin E was performed in apparently healthy women with no indication or contraindication to aspirin therapy and no history of asthma at study entry. Female health professionals self-reported an asthma diagnosis on yearly questionnaires.

Re

SUBMITTER: Kurth T 

PROVIDER: S-EPMC2631398 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature