Comparison of clinical manifestations in Alzheimer disease and dementia with Lewy bodies.

ABSTRACT:

Background

The clinical delineation of dementia with Lewy bodies (DLB) from Alzheimer disease (AD) remains unclear.

Objectives

To compare neuropsychological profiles in DLB and AD among Caribbean Hispanic family members and participants in a population-based epidemiologic sample using extended neuropsychological test batteries and to explore whether these differences were related to heritable factors.

Design

Cross-sectional study.

Setting

Clinics in northern Manhattan (New York City), the Dominican Republic, and Puerto Rico.

Patients

We compared measures of memory, orientation, language, and executive and visuospatial functioning between patients with DLB vs AD in 2 Caribbean Hispanic cohorts, including a family sample (89 patients with DLB and 118 patie

SUBMITTER: Nervi A 

PROVIDER: S-EPMC2633487 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature