Tissue remodeling: a mating-induced differentiation program for the Drosophila oviduct.

ABSTRACT:

Background

In both vertebrates and invertebrates, the oviduct is an epithelial tube surrounded by visceral muscles that serves as a conduit for gamete transport between the ovary and uterus. While Drosophila is a model system for tubular organ development, few studies have addressed the development of the fly's oviduct. Recent studies in Drosophila have identified mating-responsive genes and proteins whose levels in the oviduct are altered by mating. Since many of these molecules (e.g. Muscle LIM protein 84B, Coracle, Neuroglian) have known roles in the differentiation of muscle and epithelia of other organs, mating may trigger similar differentiation events in the oviduct. This led us to hypothesize that mating mediates the last stages of oviduct differentiation in which organ-spe

SUBMITTER: Kapelnikov A 

PROVIDER: S-EPMC2636784 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature