The fate of the duplicated androgen receptor in fishes: a late neofunctionalization event?

ABSTRACT:

Background

Based on the observation of an increased number of paralogous genes in teleost fishes compared with other vertebrates and on the conserved synteny between duplicated copies, it has been shown that a whole genome duplication (WGD) occurred during the evolution of Actinopterygian fish. Comparative phylogenetic dating of this duplication event suggests that it occurred early on, specifically in teleosts. It has been proposed that this event might have facilitated the evolutionary radiation and the phenotypic diversification of the teleost fish, notably by allowing the sub- or neo-functionalization of many duplicated genes.

Results

In this paper, we studied in a wide range of Actinopterygians the duplication and fate of the androgen receptor (AR, NR3C4), a nuclear rec

SUBMITTER: Douard V 

PROVIDER: S-EPMC2637867 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature