Bilateral subthalamic stimulation impairs cognitive-motor performance in Parkinson's disease patients.

ABSTRACT: Deep brain stimulation (DBS) is a surgical procedure that has been shown effective in improving the cardinal motor signs of advanced Parkinson's disease, however, declines in cognitive function have been associated with bilateral subthalamic nucleus (STN) DBS. Despite the fact that most activities of daily living clearly have motor and cognitive components performed simultaneously, postoperative assessments of cognitive and motor function occur, in general, in isolation of one another. The primary aim of this study was to determine the effects of unilateral and bilateral STN DBS on upper extremity motor function and cognitive performance under single- and dual-task conditions in advanced Parkinson's disease patients. Data were collected from eight advanced Parkinson's disease patients betw

SUBMITTER: Alberts JL 

PROVIDER: S-EPMC2639204 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature