Genome-scale constraint-based modeling of Geobacter metallireducens.

ABSTRACT:

Background

Geobacter metallireducens was the first organism that can be grown in pure culture to completely oxidize organic compounds with Fe(III) oxide serving as electron acceptor. Geobacter species, including G. sulfurreducens and G. metallireducens, are used for bioremediation and electricity generation from waste organic matter and renewable biomass. The constraint-based modeling approach enables the development of genome-scale in silico models that can predict the behavior of complex biological systems and their responses to the environments. Such a modeling approach was applied to provide physiological and ecological insights on the metabolism of G. metallireducens.

Results

The genome-scale metabolic model of G. metallireducens was constructed to include 747 genes and

SUBMITTER: Sun J 

PROVIDER: S-EPMC2640342 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature