Short-term genome evolution of Listeria monocytogenes in a non-controlled environment.

ABSTRACT:

Background

While increasing data on bacterial evolution in controlled environments are available, our understanding of bacterial genome evolution in natural environments is limited. We thus performed full genome analyses on four Listeria monocytogenes, including human and food isolates from both a 1988 case of sporadic listeriosis and a 2000 listeriosis outbreak, which had been linked to contaminated food from a single processing facility. All four isolates had been shown to have identical subtypes, suggesting that a specific L. monocytogenes strain persisted in this processing plant over at least 12 years. While a genome sequence for the 1988 food isolate has been reported, we sequenced the genomes of the 1988 human isolate as well as a human and a food isolate from the 2000 outbr

SUBMITTER: Orsi RH 

PROVIDER: S-EPMC2642827 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature