Molecular signature of hypersaline adaptation: insights from genome and proteome composition of halophilic prokaryotes.

ABSTRACT:

Background

Halophilic prokaryotes are adapted to thrive in extreme conditions of salinity. Identification and analysis of distinct macromolecular characteristics of halophiles provide insight into the factors responsible for their adaptation to high-salt environments. The current report presents an extensive and systematic comparative analysis of genome and proteome composition of halophilic and non-halophilic microorganisms, with a view to identify such macromolecular signatures of haloadaptation.

Results

Comparative analysis of the genomes and proteomes of halophiles and non-halophiles reveals some common trends in halophiles that transcend the boundary of phylogenetic relationship and the genomic GC-content of the species. At the protein level, halophilic species are char

SUBMITTER: Paul S 

PROVIDER: S-EPMC2643941 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature