Multiple RNAs from the mouse carboxypeptidase M locus: functional RNAs or transcription noise?

ABSTRACT:

Background

A major effort of the scientific community has been to obtain complete pictures of the genomes of many organisms. This has been accomplished mainly by annotation of structural and functional elements in the genome sequence, a process that has been centred in the gene concept and, as a consequence, biased toward protein coding sequences. Recently, the explosion of transcriptome data generated and the discovery of many functional non-protein coding RNAs have painted a more detailed and complex scenario for the genome. Here we analyzed the mouse carboxypeptidase M locus in this broader perspective in order to define the mouse CPM gene structure and evaluate the existence of other transcripts from the same genomic region.

Results

Bioinformatic analysis of nucleotide s

SUBMITTER: Guimaraes AO 

PROVIDER: S-EPMC2644694 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature