Survey of microsatellite clustering in eight fully sequenced species sheds light on the origin of compound microsatellites.

ABSTRACT:

Background

Compound microsatellites are a special variation of microsatellites in which two or more individual microsatellites are found directly adjacent to each other. Until now, such composite microsatellites have not been investigated in a comprehensive manner.

Results

Our in silico survey of microsatellite clustering in genomes of Homo sapiens, Maccaca mulatta, Mus musculus, Rattus norvegicus, Ornithorhynchus anatinus, Gallus gallus, Danio rerio and Drosophila melanogaster revealed an unexpected high abundance of compound microsatellites. About 4 - 25% of all microsatellites could be categorized as compound microsatellites. Compound microsatellites are approximately 15 times more frequent than expected under the assumption of a random distribution of microsatellites. In

SUBMITTER: Kofler R 

PROVIDER: S-EPMC2644718 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature