Health-related quality of life and patient-reported outcomes in pulmonary arterial hypertension.

ABSTRACT: Advances in our understanding of the basic pathophysiology of pulmonary arterial hypertension (PAH) has led to an expanding number of therapeutic options. The ultimate goals of therapy are to lengthen survival while improving symptoms and quality of life. A wealth of research in other conditions has established health-related quality of life (HRQoL) to be an important clinical endpoint. Until recently, however, little was known about HRQoL in PAH, and how best to measure it. Over the past few years, several studies have begun contributing to this growing area of research. Instruments used to assess HRQoL have varied between studies. The extent to which these instruments are valid in PAH depend on their specific measurement properties. In this article, we provide an overview of the differen

SUBMITTER: Chen H 

PROVIDER: S-EPMC2645237 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature