Survival following primary androgen deprivation therapy among men with localized prostate cancer.

ABSTRACT:

Context

Despite a lack of data, increasing numbers of patients are receiving primary androgen deprivation therapy (PADT) as an alternative to surgery, radiation, or conservative management for the treatment of localized prostate cancer.

Objective

To evaluate the association between PADT and survival in elderly men with localized prostate cancer.

Design, setting, and patients

A population-based cohort study of 19,271 men aged 66 years or older receiving Medicare who did not receive definitive local therapy for clinical stage T1-T2 prostate cancer. These patients were diagnosed in 1992-2002 within predefined US geographical areas, with follow-up through December 31, 2006, for all-cause mortality and through December 31, 2004, for prostate cancer-specific mortality. Inst

SUBMITTER: Lu-Yao GL 

PROVIDER: S-EPMC2645653 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature