Bimodal distribution of glucose is not universally useful for diagnosing diabetes.

ABSTRACT:

Objective

Bimodality in the distribution of glucose has been used to define the cut point for the diagnosis of diabetes. Previous studies on bimodality have primarily been in populations with a high prevalence of type 2 diabetes, including one study in a white Caucasian population. All studies included participants with known diabetes. The aim of this study was to assess whether a bimodal structure is a general phenomenon in fasting plasma glucose (FPG) and 2-h plasma glucose that is useful for deriving a common cut point for diabetes in populations of different origin, both including and excluding known diabetes.

Research design and methods

The Evaluation of Screening and Early Detection Strategies for Type 2 Diabetes and Impaired Glucose Tolerance (DETECT-2) project is an

SUBMITTER: Vistisen D 

PROVIDER: S-EPMC2646016 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature