Coordinations between gene modules control the operation of plant amino acid metabolic networks.

ABSTRACT:

Background

Being sessile organisms, plants should adjust their metabolism to dynamic changes in their environment. Such adjustments need particular coordination in branched metabolic networks in which a given metabolite can be converted into multiple other metabolites via different enzymatic chains. In the present report, we developed a novel "Gene Coordination" bioinformatics approach and use it to elucidate adjustable transcriptional interactions of two branched amino acid metabolic networks in plants in response to environmental stresses, using publicly available microarray results.

Results

Using our "Gene Coordination" approach, we have identified in Arabidopsis plants two oppositely regulated groups of "highly coordinated" genes within the branched Asp-family network of

SUBMITTER: Less H 

PROVIDER: S-EPMC2646696 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature