Imines that react with phenols in water over a wide pH range.

ABSTRACT: Cyclic imine derivatives that react with phenols, including tyrosine residues of peptides, have been developed. Reactions of the imines with phenols proceeded in water over a wide pH range (pH 2-10) at room temperature to 37 degrees C and afforded Mannich products without the need of additional catalysts.

SUBMITTER: Minakawa M 

PROVIDER: S-EPMC2647331 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature