SNPnexus: a web database for functional annotation of newly discovered and public domain single nucleotide polymorphisms.

ABSTRACT:

Motivation

Design a new computational tool allowing scientists to functionally annotate newly discovered and public domain single nucleotide polymorphisms in order to help in prioritizing targets in further disease studies and large-scale genotyping projects.

Summary

SNPnexus database provides functional annotation for both novel and public SNPs. Possible effects on the transcriptome and proteome levels are characterized and reported from five major annotation systems providing the most extensive information on alternative splicing. Additional information on HapMap genotype and allele frequency, overlaps with potential regulatory elements or structural variations as well as related genetic diseases can be also retrieved. The SNPnexus database has a user-friendly web interfac

SUBMITTER: Chelala C 

PROVIDER: S-EPMC2647830 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature