Six-minute-walk distance predicts waiting list survival in idiopathic pulmonary fibrosis.

ABSTRACT:

Rationale

Functional studies may be useful to predict survival in idiopathic pulmonary fibrosis (IPF). Various cutoffs of 6-min-walk distance (6MWD) have been suggested to identify patients at a high risk of death.

Objectives

To examine the association between 6MWD and survival in patients with IPF listed for lung transplantation, and to identify sensitive and specific cutoffs for predicting death at 6 mo.

Methods

We performed a retrospective cohort study of 454 patients classified as having IPF listed for lung transplantation with the United Network for Organ Sharing between June 30, 2004 and July 22, 2005.

Measurements and main results

Lower 6MWD was associated with an increased mortality rate (p value for linear trend < 0.0001). Patients with a walk distance

SUBMITTER: Lederer DJ 

PROVIDER: S-EPMC2648057 | biostudies-literature | 2006 Sep

REPOSITORIES: biostudies-literature