Widely conserved recombination patterns among single-stranded DNA viruses.

ABSTRACT: The combinatorial nature of genetic recombination can potentially provide organisms with immediate access to many more positions in sequence space than can be reached by mutation alone. Recombination features particularly prominently in the evolution of a diverse range of viruses. Despite rapid progress having been made in the characterization of discrete recombination events for many species, little is currently known about either gross patterns of recombination across related virus families or the underlying processes that determine genome-wide recombination breakpoint distributions observable in nature. It has been hypothesized that the networks of coevolved molecular interactions that define the epistatic architectures of virus genomes might be damaged by recombination and therefore th

SUBMITTER: Lefeuvre P 

PROVIDER: S-EPMC2648288 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature