VASCo: computation and visualization of annotated protein surface contacts.

ABSTRACT:

Background

Structural data from crystallographic analyses contain a vast amount of information on protein-protein contacts. Knowledge on protein-protein interactions is essential for understanding many processes in living cells. The methods to investigate these interactions range from genetics to biophysics, crystallography, bioinformatics and computer modeling. Also crystal contact information can be useful to understand biologically relevant protein oligomerisation as they rely in principle on the same physico-chemical interaction forces. Visualization of crystal and biological contact data including different surface properties can help to analyse protein-protein interactions.

Results

VASCo is a program package for the calculation of protein surface properties and the vis

SUBMITTER: Steinkellner G 

PROVIDER: S-EPMC2649047 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature