Hormone effects on fMRI and cognitive measures of encoding: importance of hormone preparation.

ABSTRACT: We compared fMRI and cognitive data from nine hormone therapy (HT)-naive women with data from women exposed to either opposed conjugated equine estrogens (CEE) (n = 10) or opposed estradiol (n = 4). Exposure to either form of HT was associated with healthier fMRI response; however, CEE-exposed women exhibited poorer memory performance than either HT-naive or estradiol-exposed subjects. These preliminary findings emphasize the need to characterize differential neural effects of various HTs.

SUBMITTER: Gleason CE 

PROVIDER: S-EPMC2650493 | biostudies-literature | 2006 Dec

REPOSITORIES: biostudies-literature