Mobilization of qnrB2 and ISCR1 in plasmids.

ABSTRACT: The DNA sequences of two IncHI2 plasmids, pEC-IMP and pEC-IMPQ, from metallo-beta-lactamase-producing Enterobacter cloacae clinical isolates were determined. The two conjugative plasmids are almost identical, but pEC-IMPQ carries an additional segment containing an orf513 (ISCR1), a truncated 3' conserved sequence, and a qnrB2. Comparative analyses provide support for the proposed ISCR1-mediated gene mobilization.

SUBMITTER: Chen YT 

PROVIDER: S-EPMC2650544 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature