Endothelial dysfunction induced by post-prandial lipemia: complete protection afforded by high-intensity aerobic interval exercise.

ABSTRACT:

Objectives

This study was designed to study the effect of exercise and a high-fat meal (HFM) on endothelial function.

Background

Post-prandial lipemia and exercise oppose each other in terms of cardiovascular risk; however, the mechanism of their interaction is not well understood.

Methods

Endothelial function was assessed by brachial artery flow-mediated dilation (FMD) in 8 healthy men before and after an HFM preceded (16 to 18 h) by rest, a single bout of continuous moderate-intensity exercise (CME), and high-intensity interval exercise (HIIE).

Results

Before the HFM, initial brachial artery diameters were similar in all trials (0.43 +/- 0.04 cm), but after the HFM, basal diameter decreased only in the control (0.39 +/- 0.03 cm) and CME (0.38 +/- 0.04 cm) tri

SUBMITTER: Tyldum GA 

PROVIDER: S-EPMC2650775 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature