Performance of microcalorimetry for early detection of methicillin resistance in clinical isolates of Staphylococcus aureus.

ABSTRACT: We describe a calorimetric assay for the detection of methicillin-resistant Staphylococcus aureus (MRSA) within 5 h. Microbial heat was calculated in culture with and without cefoxitin. Among 30 genetically distinct clinical isolates, 19/20 MRSA (95%) and 10/10 methicillin-susceptible Staphylococcus aureus (100%) were correctly identified. Microcalorimetry may be useful for rapid MRSA screening.

SUBMITTER: Baldoni D 

PROVIDER: S-EPMC2650961 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature