Detection and toxin typing of Clostridium perfringens in formalin-fixed, paraffin-embedded tissue samples by PCR.

ABSTRACT: Since current microbiology methods are not suitable to detect Clostridium perfringens in formalin-fixed, paraffin-embedded tissue samples, we developed a PCR assay to detect toxin-encoding genes and the 16S rRNA gene of C. perfringens. We successfully detected and genotyped C. perfringens in tissue sections from two autopsy cases.

SUBMITTER: Wu J 

PROVIDER: S-EPMC2650962 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature