Motivated proteins: a web application for studying small three-dimensional protein motifs.

ABSTRACT:

Background

Small loop-shaped motifs are common constituents of the three-dimensional structure of proteins. Typically they comprise between three and seven amino acid residues, and are defined by a combination of dihedral angles and hydrogen bonding partners. The most abundant of these are alphabeta-motifs, asx-motifs, asx-turns, beta-bulges, beta-bulge loops, beta-turns, nests, niches, Schellmann loops, ST-motifs, ST-staples and ST-turns. We have constructed a database of such motifs from a range of high-quality protein structures and built a web application as a visual interface to this.

Description

The web application, Motivated Proteins, provides access to these 12 motifs (with 48 sub-categories) in a database of over 400 representative proteins. Queries can be made for

SUBMITTER: Leader DP 

PROVIDER: S-EPMC2651126 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature