Impact of breed and sex on porcine endocrine transcriptome: a bayesian biometrical analysis.

ABSTRACT:

Background

Transcriptome variability is due to genetic and environmental causes, much like any other complex phenotype. Ascertaining the transcriptome differences between individuals is an important step to understand how selection and genetic drift may affect gene expression. To that end, extant divergent livestock breeds offer an ideal genetic material.

Results

We have analyzed with microarrays five tissues from the endocrine axis (hypothalamus, adenohypophysis, thyroid gland, gonads and fat tissue) of 16 pigs from both sexes pertaining to four extreme breeds (Duroc, Large White, Iberian and a cross with SinoEuropean hybrid line). Using a Bayesian linear model approach, we observed that the largest breed variability corresponded to the male gonads, and was larger than at t

SUBMITTER: Perez-Enciso M 

PROVIDER: S-EPMC2656523 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature