Systematic identification of genes involved in divergent skeletal muscle growth rates of broiler and layer chickens.

ABSTRACT:

Background

The genetic closeness and divergent muscle growth rates of broilers and layers make them great models for myogenesis study. In order to discover the molecular mechanisms determining the divergent muscle growth rates and muscle mass control in different chicken lines, we systematically identified differentially expressed genes between broiler and layer skeletal muscle cells during different developmental stages by microarray hybridization experiment.

Results

Taken together, 543 differentially expressed genes were identified between broilers and layers across different developmental stages. We found that differential regulation of slow-type muscle gene expression, satellite cell proliferation and differentiation, protein degradation rate and genes in some metabolic

SUBMITTER: Zheng Q 

PROVIDER: S-EPMC2656524 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature