Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis.

ABSTRACT:

Background

Streptococcus uberis, a Gram positive bacterial pathogen responsible for a significant proportion of bovine mastitis in commercial dairy herds, colonises multiple body sites of the cow including the gut, genital tract and mammary gland. Comparative analysis of the complete genome sequence of S. uberis strain 0140J was undertaken to help elucidate the biology of this effective bovine pathogen.

Results

The genome revealed 1,825 predicted coding sequences (CDSs) of which 62 were identified as pseudogenes or gene fragments. Comparisons with related pyogenic streptococci identified a conserved core (40%) of orthologous CDSs. Intriguingly, S. uberis 0140J displayed a lower number of mobile genetic elements when compared with other pyogenic streptococci, however bacterio

SUBMITTER: Ward PN 

PROVIDER: S-EPMC2657157 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature