Common variant in myocilin gene is associated with high myopia in isolated population of Korcula Island, Croatia.

ABSTRACT:

Aim

To study the association between genetic variants in myocilin and collagen type I alpha 1 genes and high myopia in an isolated island population.

Methods

A total of 944 examinees from the genetic epidemiology study conducted on the island of Korcula, Croatia, were included in the study. We selected 2 short nucleotide polymorphisms (SNP) available in our genome-wide scan set of SNPs that were previously associated with high myopia and used them to replicate previous claims of possible association.

Results

Nineteen cases of high myopia, defined as the refraction of

SUBMITTER: Vatavuk Z 

PROVIDER: S-EPMC2657568 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature