Risk of adverse birth outcome and miscarriage in pregnant users of non-steroidal anti-inflammatory drugs: population based observational study and case-control study.

ABSTRACT:

Objective

To estimate the risk of adverse birth outcome in women who take non-steroidal anti-inflammatory drugs during pregnancy.

Design and setting

Population based cohort study and a case-control study, both based on data from a prescription registry, the Danish birth registry, and one county's hospital discharge registry.

Participants

COHORT STUDY: 1462 pregnant women who had taken up prescriptions for non-steroidal anti-inflammatory drugs in the period from 30 days before conception to birth and 17 259 pregnant women who were not prescribed any drugs during pregnancy. CASE-CONTROL STUDY: 4268 women who had miscarriages, of whom 63 had taken non-steroidal anti-inflammatory drugs, and 29 750 primiparous controls who had live births.

Main outcome measures

Inci

SUBMITTER: Nielsen GL 

PROVIDER: S-EPMC26578 | biostudies-literature | 2001 Feb

REPOSITORIES: biostudies-literature