Prevalence of abnormal lipid profiles and the relationship with the development of microalbuminuria in adolescents with type 1 diabetes.

ABSTRACT:

Objective

To explore the prevalence of lipid abnormalities and their relationship with albumin excretion and microalbuminuria in adolescents with type 1 diabetes.

Research design and methods

The study population comprised 895 young subjects with type 1 diabetes (490 males); median age at the baseline assessment was 14.5 years (range 10-21.1), and median diabetes duration was 4.8 years (0.2-17). A total of 2,194 nonfasting blood samples were collected longitudinally for determination of total cholesterol, LDL cholesterol, HDL cholesterol, TG, and non-HDL cholesterol. Additional annually collected data on anthropometric parameters, A1C, and albumin-to-creatinine ratio (ACR) were available.

Results

Total cholesterol, LDL cholesterol, HDL cholesterol, and non-HDL choleste

SUBMITTER: Marcovecchio ML 

PROVIDER: S-EPMC2660471 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature