Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity.

ABSTRACT:

Background

Originating from Africa, India, and the Middle East, frankincense oil has been important both socially and economically as an ingredient in incense and perfumes for thousands of years. Frankincense oil is prepared from aromatic hardened gum resins obtained by tapping Boswellia trees. One of the main components of frankincense oil is boswellic acid, a component known to have anti-neoplastic properties. The goal of this study was to evaluate frankincense oil for its anti-tumor activity and signaling pathways in bladder cancer cells.

Methods

Frankincense oil-induced cell viability was investigated in human bladder cancer J82 cells and immortalized normal bladder urothelial UROtsa cells. Temporal regulation of frankincense oil-activated gene expression in bladder canc

SUBMITTER: Frank MB 

PROVIDER: S-EPMC2664784 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature