Reconstruction of metabolic pathways for the cattle genome.

ABSTRACT:

Background

Metabolic reconstruction of microbial, plant and animal genomes is a necessary step toward understanding the evolutionary origins of metabolism and species-specific adaptive traits. The aims of this study were to reconstruct conserved metabolic pathways in the cattle genome and to identify metabolic pathways with missing genes and proteins. The MetaCyc database and PathwayTools software suite were chosen for this work because they are widely used and easy to implement.

Results

An amalgamated cattle genome database was created using the NCBI and Ensembl cattle genome databases (based on build 3.1) as data sources. PathwayTools was used to create a cattle-specific pathway genome database, which was followed by comprehensive manual curation for the reconstruction of

SUBMITTER: Seo S 

PROVIDER: S-EPMC2669051 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature