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Estimation of proteinuria as a predictor of complications of pre-eclampsia: a systematic review.


ABSTRACT:

Background

Proteinuria is one of the essential criteria for the clinical diagnosis of pre-eclampsia. Increasing levels of proteinuria is considered to be associated with adverse maternal and fetal outcomes. We aim to determine the accuracy with which the amount of proteinuria predicts maternal and fetal complications in women with pre-eclampsia by systematic quantitative review of test accuracy studies.

Methods

We conducted electronic searches in MEDLINE (1951 to 2007), EMBASE (1980 to 2007), the Cochrane Library (2007) and the MEDION database to identify relevant articles and hand-search of selected specialist journals and reference lists of articles. There were no language restrictions for any of these searches. Two reviewers independently selected those articles in which

SUBMITTER: Thangaratinam S 

PROVIDER: S-EPMC2670320 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature