Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC2673547 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Cancer cell 20090301 3
Pancreatic cancer is a deadly disease characterized by late diagnosis and resistance to therapy. Much progress has been made in defining gene defects in pancreatic cancer, but a full accounting of its molecular pathogenesis remains to be provided. Here, we show that expression of the ataxia-telangiectasia group D complementing gene (ATDC), also called TRIM29, is elevated in most invasive pancreatic cancers and pancreatic cancer precursor lesions. ATDC promoted cancer cell proliferation in vitro ...[more]