Comprehensive treatment of extensively drug-resistant tuberculosis.

ABSTRACT:

Background

Extensively drug-resistant tuberculosis has been reported in 45 countries, including countries with limited resources and a high burden of tuberculosis. We describe the management of extensively drug-resistant tuberculosis and treatment outcomes among patients who were referred for individualized outpatient therapy in Peru.

Methods

A total of 810 patients were referred for free individualized therapy, including drug treatment, resective surgery, adverse-event management, and nutritional and psychosocial support. We tested isolates from 651 patients for extensively drug-resistant tuberculosis and developed regimens that included five or more drugs to which the infecting isolate was not resistant.

Results

Of the 651 patients tested, 48 (7.4%) had extensively

SUBMITTER: Mitnick CD 

PROVIDER: S-EPMC2673722 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature