A robust linkage map of the porcine autosomes based on gene-associated SNPs.

ABSTRACT:

Background

Genetic linkage maps are necessary for mapping of mendelian traits and quantitative trait loci (QTLs). To identify the actual genes, which control these traits, a map based on gene-associated single nucleotide polymorphism (SNP) markers is highly valuable. In this study, the SNPs were genotyped in a large family material comprising more than 5,000 piglets derived from 12 Duroc boars crossed with 236 Danish Landrace/Danish Large White sows. The SNPs were identified in sequence alignments of 4,600 different amplicons obtained from the 12 boars and containing coding regions of genes derived from expressed sequence tags (ESTs) and genomic shotgun sequences.

Results

Linkage maps of all 18 porcine autosomes were constructed based on 456 gene-associated and six porcine E

SUBMITTER: Vingborg RK 

PROVIDER: S-EPMC2674067 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature