NMR assignment of polymerase beta labeled with 2H, 13C, and 15N in complex with substrate DNA.

ABSTRACT: DNA polymerase beta is a multifunctional enzyme involved in base excision repair of nuclear DNA invertebrate cells. We present here the first assignments of the full-length protein (335 residues, 39 kDa) in the presence of a double gap--double hairpin DNA (22 nucleotides, 7 kDa).

SUBMITTER: Mueller GA 

PROVIDER: S-EPMC2676717 | biostudies-literature | 2007 Jul

REPOSITORIES: biostudies-literature