Medical decision-making capacity in mild cognitive impairment: a 3-year longitudinal study.

ABSTRACT:

Objective

To investigate longitudinal change in the medical decision-making capacity (MDC) of patients with amnestic mild cognitive impairment (MCI) under different consent standards.

Methods

Eighty-eight healthy older controls and 116 patients with MCI were administered the Capacity to Consent to Treatment Instrument at baseline and at 1 to 3 (mean = 1.7) annual follow-up visits thereafter. Covariate-adjusted random coefficient regressions were used to examine differences in MDC trajectories across MCI and control participants, as well as to investigate the impact of conversion to Alzheimer disease on MCI patients' MDC trajectories.

Results

At baseline, MCI patients performed significantly below controls only on the three clinically relevant standards of appreciation

SUBMITTER: Okonkwo OC 

PROVIDER: S-EPMC2676965 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature