Etiology of musician's dystonia: familial or environmental?

ABSTRACT:

Objective

To test the hypothesis that there is familial aggregation of dystonia and other movement disorders in relatives of patients with musician's dystonia (MD) and to identify possible environmental triggers.

Methods

The families of 28 index patients with MD (14 with a reported positive family history of focal task-specific dystonia [FTSD] and 14 with no known family history [FH-]) underwent a standardized telephone screening interview using a modified version of the Beth Israel Dystonia Screen. Videotaped neurologic examinations were performed on all participants who screened positive and consensus diagnoses established. All patients were investigated for DYT1 dystonia and suitable families were tested for linkage to DYT7. All family members were administered questionna

SUBMITTER: Schmidt A 

PROVIDER: S-EPMC2677486 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature