Comparative genomics of Enterococcus faecalis from healthy Norwegian infants.

ABSTRACT:

Background

Enterococcus faecalis, traditionally considered a harmless commensal of the intestinal tract, is now ranked among the leading causes of nosocomial infections. In an attempt to gain insight into the genetic make-up of commensal E. faecalis, we have studied genomic variation in a collection of community-derived E. faecalis isolated from the feces of Norwegian infants.

Results

The E. faecalis isolates were first sequence typed by multilocus sequence typing (MLST) and characterized with respect to antibiotic resistance and properties associated with virulence. A subset of the isolates was compared to the vancomycin resistant strain E. faecalis V583 (V583) by whole genome microarray comparison (comparative genomic hybridization (CGH)). Several of the putative enterococ

SUBMITTER: Solheim M 

PROVIDER: S-EPMC2680900 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature