Quantification of optical images of cortical responses for inferring functional maps.

ABSTRACT: Optical imaging of cortical signals enables the mapping of functional organization across large patches of cortex with good spatial resolution. But techniques for the quantitative analysis and interpretation of these images are limited. Frequently the functional architecture of the cortex is inferred from the visible topography of cortical reflectance images averaged or differenced across stimulus conditions and scaled or color-coded for presentation. Such qualitative assessments have sometimes led to divergent conclusions particularly about the organization of spatial and temporal frequency preferences in the primary visual cortex. We applied quantitative methods derived from signal detection theory to objectively interpret optical images. The differential response to any two arbitrary st

SUBMITTER: Purushothaman G 

PROVIDER: S-EPMC2681427 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature